Biology Story Ideas

DNA - illustration for biological story ideas article

Looking to write a story about sex and sexuality? How about cloning, genetic engineering, or immortality? Explore this story ideas collection and get mutating!

Sex

Gender – Want Some Butter For Those Gender Rolls?

  • In a society where women are in charge, boys are taught from infancy that having opinions or trying to make your own decisions is “effeminate” and “girly”. Any attempt at a male rebellion is quickly defeated by teasing and mockery.
  • In the distant future, humans are born agender but pick their gender in college, like a major.
  • A medical research company genetically engineers a group of children who are both sexes. How will they behave? How will the children dress? How will they interact with single-sexed people?
  • After the invention of the artificial womb, prospective parents have arguments about which one of them will carry the baby.
  • After being denied a job, a young man sues a fertility clinic for his right to become the first male surrogate “mother.” A judge’s ruling forces the fertility clinic to implant him with an artificial womb.
  • In the distant future, evolution dramatically changes the meaning of gender. When humans gather in groups, individuals change gender until there is an even mix of males and females. Cocktail parties become an unpredictable mass of shifting relationships.
  • After World War III, the female survivors decide that, as men caused the war and did most of the fighting, it is simply too dangerous to allow them to be in control of the governments any longer. Men are banned from government and military service and, after a few years, banned from voting, having an education, or having a job outside the home. A young boy, depressed by his limited prospects at home, decides to pose as a girl so he can join the navy.

Polyamory – When You Find Your Special Someones

  • Earth sends a spaceship full of colonists to a new planet. In order to populate the new world as quickly as possible, they send ten women for every man. Some women adjust, adapt to the new culture, accepting their role as one wife of many. Other women flee the colony and have to fend for themselves on the new planet.
  • Aliens attack the Earth and take the majority of the women back to their planet to be part of their interspecies breeding program. The remaining women are left with their pick of mates. Some become incredibly choosy, dating one perfect male. Some women marry multiple husbands, with a new man for every day of the week.
  • An outbreak of a new virus makes all the men on Earth infertile. A new fertility treatment solves the problem by creating two kinds of males: “A” and “B.” Women must sleep with both types to become pregnant.

Sexuality And Procreation – Copulating and Fornicating

  • The passengers of a generation ship discover that they aren’t actually in space. They are still on Earth, being used in a secret government breeding program. They search for a way to escape without alerting the “ship’s” crew.
  • A disease renders all the women infertile. Scientists genetically engineer women who are super-fertile, like human insect queens.
  • After the invention of artificial sperm, women start to view men as unnecessary
  • A medical research firm invents an artificial womb. Soon procreation is outlawed. Instead of sexual reproduction, corporations grow genetically engineered “perfect” babies and sell them on the open market.
  • An outbreak of disease kills everyone under twenty years old. Doctors discover that the only way to keep babies from dying is if they extend the length of the gestation period from nine months to twelve years
  • A bachelor is discovered to have a rare mutation that would make all of his offspring geniuses, physically beautiful, and nearly immortal. His sperm becomes the most valuable substance on earth.
  • Wanting to destroy the US economy, a terrorist group designs a “baby bomb,” a device that will keep women continuously pregnant
  • On a distant world, the land is filled with men. Once a year, the men journey to the beach, where they encounter the only females on the planet: mermaids.
  • On a distant planet, the corner bar is the most stressful place a man can be. Men approach women knowing that, if their pickup lines fail, the robot guards will drag them outside and beat them to death.
  • A race of aliens takes control of planet after planet, not through warfare, but through breeding. The aliens have airborne spores which can get any females pregnant with an alien baby. The babies are so adorable that any female would feel compelled to raise them as one of her own. The aliens fill the earth’s atmosphere with their spores, and simply wait for their offspring to grow up and overwhelm humanity through sheer numbers.
  • After researching reincarnation, a man discovers a way to be reborn but retain his memory of his old life. After a particularly passionate night of lovemaking, he has a heart attack and dies. A few months later, the man is reincarnated… as his own infant son.

DNA

Genetic Engineering – Chromosomes and Then Some

  • Scientists genetically engineer a new breed of human that can survive on the surface of Mars. The “Martians” grow to hate their barren world and the home planet they cannot survive on.
  • A genetics company hires a group of women to be surrogate mothers. They are required to live in a dormitory for nine months where their fetuses can be constantly monitored. One of the women starts a secret affair with the head doctor. Eventually, she convinces the doctor to give her the details of the experiment. The women have been impregnated with genetically engineered human/ape hybrids.
  • A genetic experiment lets humans enter cryptobiosis. This is a boon for space travel, as humans can now be frozen on Earth and thawed out on planets thousands of years later. However, it also makes the space travelers obsessed with cold. They vow to return, bringing Earth a new ice age.
  • When you’re traveling faster than the speed of light, you absolutely, positively must know about any objects in your path so you can chart a course around them. Space defense relies on this fact. When you detect ships headed your way, the best thing to do is put something in their path – asteroids, mines, even other ships if you have to. Rumor has it that the enemy has genetically engineered a pilot fast enough to dodge any obstacle, but don’t worry about that. What harm could one pilot do?
  • Genetic engineering and plastic surgery become so advanced that humans can take on any appearance. A new dating service specializes in helping altered humans find the perfect partner. Are you a centaur who loves women with tails and cat ears? They’ve got you covered!
  • In order to eliminate the need for food supplies on long space voyages, researchers create a virus that allows humans to photosynthesize. In addition to green skin, the virus comes with some unfortunate side effects. The infected humans become more and more plantlike, growing to hate and fear normal humans. They develop a plan to rid the world of the “meat eaters”.
  • A pregnant couple decides that they want their little angel to look the part – a little genetic tampering gives them an infant with wings
  • After exploring the far reaches of the universe, humans discover very few earth-like planets. Scientists try to create new breeds of humans that can survive in inhospitable planets
  • Omicron Unlimited offers prospective parents an invaluable service: by genetically altering their embryos, the company can insure that their children will be intelligent, attractive, and healthy. Twenty years later, the genetically-altered children are ready to have children of their own. However, there is a problem: Omicron Unlimited owns their DNA. They have to purchase the right to reproduce.
  • Variation: Omicron Unlimited engineers the children with self-destructing genes. They will die on their twenty-first birthdays, unless they pay for special medication. And, of course, the pills are very, very expensive…
  • A medical research company gives an extra boost of intelligence to monkeys, so they can work as servants to humans. Unfortunately, the new line of apes might be a little bit too smart…
  • A group of male scientists works secretly to genetically engineer a line of very beautiful but very unintelligent human females – When their plan is discovered and made public, they receive both support and condemnation.
  • The government, struggling to attract employees for low-level jobs, genetically engineers a new breed of human that are unable to feel boredom.
  • After years of protests by animal rights activists, a meat packing plant genetically engineers a new breed of pigs that slaughter themselves.
  • Genetic experiments with parrots lead to a dramatic increase in their intelligence. The parrots escape the lab and reproduce, becoming as common as sparrows. Eventually, suburbanites cannot leave the house without having insults and criticisms hurled at them from the trees.

Cloning – All By Myselves…

  • A couple is on a road trip. They pull off the highway to find food and a hotel room for the night. Oddly, everyone they encounter appears to be the same person. The hotel receptionist looks just like the waiter at the restaurant, just with a mustache and a different haircut. Whenever they mention the resemblance, everyone denies knowing anything about it. The couple decides to delay their trip until they get to the bottom of this mystery.
  • A scientist is experimenting with human cloning when the process goes horribly wrong. His cloned cells grow into an eye. Rather than growing the rest of the body, the eye gets bigger and bigger. Using its optic nerves like octopus tentacles, it smashes the cloning tank and escapes.
  • After losing a limb in an accident, a man has a new arm grown from cloned tissue. The cloned arm develops a mind of its own and escapes the lab before it can be attached.
  • Thanks to cloning and mind transfer technology, people can now become a copy of their favorite celebrity. Celebrities are careful to destroy anything that might have a trace of their DNA on it so that they cannot be cloned without their permission.
  • Aliens abduct a young man and perform cloning experiments on him. They return him to Earth, along with a clone. The young man is startled to realize that his consciousness is inside both bodies. They are both equally him. He/they go home and look for a way to hide his/their two bodies from his/their family and friends.
  • A death cult searches for a way to conduct their rituals without the constant police investigations. They hire a group of geneticists to set up a cloning lab and grow victims for human sacrifices. A group of clones escapes the lab and searches for help, but the cult’s influence is everywhere. Who can they trust?
  • A spelunker ventures in to a cave system and discovers a hidden cloning laboratory. Giant, cylindrical tanks hold clones in various stages of growth. As the spelunker looks closer, he realizes these are all clones of celebrities. Before he can investigate any further, the scientist returns…
  • A woman discovers that the National Space Agency is creating clones of astronauts. For every successful mission, there are dozens of dead clones left to float in space forever. She investigates to find out what is killing the clones and why NSA is covering it up.
  • A young man joins a military starship’s crew. On his first mission, everyone else on board is killed. He discovers a cloning tank hidden away with the life support system. He clones himself many times, hoping that he and his copies can run the entire ship themselves.
  • A woman gets a job as a DNA hunter. She follows targeted individuals and retrieves used cups, napkins, toothpicks, anything that might have a trace of their DNA on it and turns it over to a mysterious corporation. When she discovers the DNA is being used to create illegal clones, she is horrified and vows to stop the corporation’s plan.
  • Afraid of assassination, a dictator has a dozen clones created to serve as body doubles. One of the clones looks for a way to escape his dangerous job and start a new life in another country. Unfortunately, international travel is difficult when you look like one of the most hated men on the planet.
  • A geneticist develops a machine that can take a cloned embryo and age it into a fully grown adult in a matter of hours. She creates a copy of herself. The next day, she returns to the lab and finds the copy has been murdered. She must solve the crime before the killer discovers that she is still alive.
  • A group of scientists are experimenting with human cloning, hoping to create decoys for the president to prevent assassination. They grow a clone, accelerate the aging process until it reaches adulthood, and install the memories and knowledge of the original. However, the process doesn’t stick. Sometimes the clones regress to infancy with the minds of adults. Other times, their minds regress while their bodies stay the same.
  • A genetics company hires a group of women to be surrogate mothers. They are required to live in a dormitory for nine months where their fetuses can be constantly monitored. One of the women breaks into her doctor’s office and discovers some confidential files. The women have been impregnated with the clones of a recently-executed serial killer.
  • A man grows up in a strange medical facility. He discovers that he is a clone. The original will have his mind digitized and uploaded into the clone body, extending his lifespan. The clone breaks into the chief neurologist’s office and learns how the uploading process works. He decides to fake the upload process and take the place of the original.
  • A geneticist learns that he has a terminal illness. He decides to replace himself with a clone, so his family won’t have to go through the pain of seeing him deteriorate. Thanks to his neurologist friend’s memory transferal technology, his clone will think it’s the original. A few months later, the geneticist unexpectedly recovers. He develops a plan to replace the clone and get his family back.
  • A CIA agent dies in the line of duty and is replaced with a clone. The clone has his memories but not his emotional state. The clone is supposed to take over the agent’s life, but he will have to pretend to love the agent’s wife and family.
  • Terrified of assassination, a dictator has himself cloned a dozen times. He plans to surround himself with decoys to draw enemy fire. However, the clones escape the lab. Each one believes he is the original and the dictator is just another clone.
  • The family of a billionaire is astounded to learn that he rewrote his will to leave everything to his clone. The family plot to murder the clone so the inheritance will be theirs.
  • A bratty ten-year-old is amazed to discover that his parents have cloned him. The clone is being grown with a microchip in its brain to make it better behaved. The child searches for a way to end the experiment before he is replaced.
  • A misanthropic scientist clones himself half a dozen times, figuring he can at least keep himself company. He soon discovers that he is harder to live with than he thought.
  • A man clones his ex-wife over and over, the marriage failing each time
  • A woman cloning her children repeatedly, keeping them as small children forever
  • A lonely man clones himself, but switches the sex chromosomes to “XX”
  • In the future, celebrities have to jealously guard their DNA, lest they be cloned without their permission
  • Variation – Celebrities sell their DNA, so that childless couples could have babies cloned from the stars.
  • Scientists develop a way for humans to be nearly immortal. Older people have their minds loaded into younger clones of themselves. A husband and wife decide to sue after a technical glitch puts them in each other’s bodies
  • Variation – A dying woman is cloned and, when her clone finally turns twenty-one, her mind is loaded into the clone’s brain. Due to a computer glitch, the clone’s mind is not erased. Both minds are trapped together in the same body.
  • A man clones himself and his parents so he can relive his childhood
  • The latest celebrity scandal involves an A-list actor who was caught in bed with his own clone.
  • Frustrated with the way the government is run, a man clones himself enough times that his vote controls every election.
  • After taking part in a strange scientific experiment, a man develops the ability to reproduce asexually like a single-celled organism.
  • The government hires an assassin to kill a scientist who is working on dangerous experiments in genetic engineering. When the assassin arrives at the scientist’s lab, he discovers that the scientist has cloned himself dozens and dozens of times.
  • Afraid of being assassinated by terrorists, the President has himself cloned half a dozen times. He feels much safer at first, but then the clones decide that they want all the political power to themselves.
  • A woman finds her husband in bed with another woman. Oddly, the “other” woman is also her.
  • Variation – A geneticist asks his wife if she would ever consider a threesome. When she agrees, she discovers that the threesome is a little different than she had imagined…

Mutation – If My Nine TVs Are Too Loud, You Can Mutate

  • A mutated fungus turns dead trees into walking abominations, wooden monsters that haunt forests and tear apart unlucky travelers. After losing his daughter to one of these creatures, an inventor heads after it with a flame thrower. The sheriff chases after him, hoping to prevent the inventor from burning down the entire forest.
  • A planet is constructed to be the ultimate destination for spelunkers. The planet has thousands of cave systems going for miles underground. To make exploring more interesting, cave-dwelling creatures are brought in: salamanders, glowworms, cave swallows, and of course bats. Chemicals used to carve out the caves cause the bats to mutate into huge, vicious killers with a taste for human flesh.
  • A lab accident mixes a veterinarian’s DNA with that of a house cat. When her husband sees her for the first time, he is completely comfortable with her new appearance. Perhaps too comfortable…
  • After being exposed to toxic waste, a handyman sprouts a third arm. At first, the new appendage comes in handy and the man is rather pleased. But then, he sprouts a fourth arm… and a fifth… and a sixth…
  • Variation – Exposure to toxic waste leaves a musician with four extra arms. He gives a whole new meaning to the phrase “one man band.”
  • A mad scientist runs an unusual “dating service.” He kidnaps women from neighboring towns and transforms them into human/animal hybrids. These exotic creatures are sold to wealthy men looking for exotic mates. The business is a success until the scientist changes a beautiful martial arts expert into a half-leopard…
  • A strange mutation in human DNA leads to a new fatal disease: boredom. The instant humans grow tired of life, they die.
  • Before he can purchase medical insurance, a man is forced to undergo a detailed examination. The doctors discover that the man’s blood contains inactive DNA in microscopic “seeds.” The DNA for thousands of extinct animals is pulsing through his veins.

Evolution – Darwin, Lose, or Draw

  • A CEO discovers that the sophisticated AI his programmers designed is actually a group of mice typing on a keyboard. When the CEO says he is shutting down the program, the super intelligent mice insist that they can replace his human programmers.
  • A planet where intelligent life evolved from insects. After sex, the women to eat their husbands.  The wedding night is hell.
  • Humans are gradually replaced by highly-evolved squirrels
  • Earth sends a sleeper ship to a distant world. Sadly, the ship’s computer malfunctions, only reviving the tubes containing the passenger’s pets. Thousands of years later, the earth develops a faster-than-light spacecraft, sending new colonists into space. They discover that the new world is controlled by the decedents of the passengers’ pets, which have evolved into intelligent bipeds.
  • Variation – A sleeper ship heads off into space for a journey that will last eons. When the ship finally arrives at the new world, the passengers are awakened, and shocked to discover that 1. The ship left earth with a cargo hold full of cockroaches and 2. The cockroaches have evolved intelligence.
  • Variation – A newlywed couple buys what they think is their dream house. However, they soon discover that 1. Their house is infested with cockroaches, 2. Their house is located atop a toxic waste dump, and 3. The cockroaches are evolving.
  • A teenager refuses to invite any of his friends over to his house, and he won’t even tell them where he lives. After arguing about it all summer, one of his friends finds out why: his parents are cavemen.
  • In the Middle Ages, humans split off into two subspecies, one with wings, one without. The winged humans can attack bomb the castles of their enemies from the sky, far out of reach of the non-winged humans’ weapons.
  • Scientists construct the most powerful computer ever build to study human evolution. The computer runs a simulation of the human life on earth, allowing them to see how humans will evolve in the future. What they discover is so horrifying they decide that humanity must be exterminated for its own good.
  • An alien comes to earth with technology that, he claims, can dramatically increase the speed of human evolution. However, the technology creates a new kind of “generation gap,” psychically gifted children who think of their parents as backward cavemen.
  • A group of scientists and politicians believe that humanity is “de-evolving.” They believe that medical care and the ease of modern life has virtually eliminated “survival of the fittest.” In order to insure that only the strongest survive, they develop a plan: bring back the dinosaurs. Only those strong and smart enough to avoid being eaten will reproduce.

Life And Death

Immortality and Life Extension – Forever Is A Long Time

  • An Earth salesman comes to a planet where the locals have everything they could possibly ever want: endless leisure time, luxurious homes, and even immortality. He attempts to sell them the one thing they don’t have: death.
  • The eternal life serum had worked! He could go on and on forever. Soon, Mary would return from Europe and he could tell her all about it. That is, if he could still speak. Most of his flesh had rotted away. He was essentially a walking skeleton. But, technically, the serum had worked.
  • A team of space explorers discovers a strange planet where nothing ever ages. They decide to keep the planet a secret and start their own, very private colony. One of the explorers begins to feel guilty, believing they are playing god and shouldn’t get to decide who will live forever on the new world and who will grow old and die on Earth. He decides to betray the others and reveal their secret.
  • A bank robber faces off against a dozen policemen. They shoot again and again, but he remains standing. He laughs. Immortality has its advantages.
  • A scientist and womanizer invents a pill that can grant humans immortality. The drug is so expensive and the ingredients so rare, he can only produce two doses. He takes one, and then debates which one of his lady friends to offer the other pill. He soon discovers that no one wants to spend eternity with him.
  • A psychologist is hired to lead a support group for depressed immortals. Vampires, sorcerers, energy beings, and other immortals discuss the pain of seeing their mortal loved ones age and die, the boredom of living for millennia, the fear of being around for the heat death of the universe, and other worries. The psychologist struggles to treat their unique problems while dealing with the temptation of seeking immortality herself.
  • After the invention of human immortality, all celebrities know they will live to see their careers die and their work forgotten. That is, everyone except one woman, who has managed to remain famous and popular for over ten thousand years. Celebrities beg for her help at holding on to fame, but she refuses to share her secret.
  • A new medicine makes humans immortal, but only the rich are able to pay for the treatments. A new game show offers immortality as the grand prize
  • A corporation offers anyone immortality, as long as they will work eighteen hours a day in one of their factories
  • A medical research firm designs a treatment that slows the aging process down to one-tenth of its current speed. Unfortunately, there is a side effect: any future children will be affected, too. The “terrible twos” now last a decade.
  • A man is cursed by his enemies with immortality. He spends hundreds of years watching his friends and family grow old and die. Tired of loss, he retreats to a cave in the wilderness, not speaking to anyone for centuries. Countless millennia later, he faces the only thing worse than grief: the heat death of the universe. If he cannot find a way to die, he will face an eternity floating in formless, empty space.
  • A new medication dramatically increases a human’s lifespan by reversing the aging process. Whenever the user falls asleep, they age in reverse.
  • A new medical treatment offers immortality, but for a price. The longer they live, the faster their memories fade.
  • A scientist develops a medication that would completely stop the aging process, making humans nearly immortal. But before it can be brought into production, he discovers that the pharmaceutical company isn’t going to sell it. They have the cure for every disease known to man but they realize it would put them out of business. They want to keep the medication for themselves. He memorizes the formula and destroys all the physical copies, leaving his laboratory in flames. He is hunted by the pharmaceutical company, the government, an aging billionaire, and a religious cult that believes that modern medicine is evil.
  • A man discovers a way to move his consciousness from body to body, becoming essentially immortal – as long as he leaves a body before it dies.
  • A medical research company develops a treatment that speeds up the healing process, making it nearly impossible for the patient to die. Decades later, a small group of scientists discovers proof of the afterlife. The immortal humans are faced with the knowledge that they will never see heaven.
  • Deep in the Amazon rain forest, explorers discover a new species of flower, which they take back to America. The leaves of the plant temporarily stop the aging process, making immortality a real possibility. However, the plant is difficult to grow. It needs lots of sun, water, and human blood.
  • An astronaut discovers the secret of immortality and heads back to earth with the good news. But, on the way back, his ship is struck by an asteroid and destroyed. The astronaut is left floating in space, immoral and alone.
  • An advanced civilization develops medical technology so advanced that people become essentially immortal. A new law is passed: instead of wasting space for prisons, criminals will simply be dropped into deep space and left to float for eternity.
  • Variation – Biological and nuclear warfare kills off most of the population, and the secret of near-immortality is lost. Slowly, society begins to rebuild. Millennia later, one of the immortal criminals finds his way back to the planet. And he’s pissed…
  • A woman discovers a way to regain her lost youth: she will transfer her mind into her teenage daughter’s body.  Twenty years later, she gets remarried and has another daughter, and the process repeats again. After ten generations, her latest daughter discovers her mother’s evil plan. The daughter must stop her mother before her sixteenth birthday, when the switchover takes place.
  • Medical science advances to the point where humans become nearly immortal. However, there is one problem: boredom. To avoid becoming bored with life, humans have their memories erased once every hundred years.
  • New suspended animation machines allow Earth’s laziest humans to daydream forever in coffin-like storage pods.

Cryonics – Crack Open A Cold One

  • A group of scientists develop suspended animation technology, hoping to sleep until humanity evolves beyond the desire for war. When they awaken, they discover that humanity is long gone and the world has been colonized by an alien species.
  • A man and his cat are cryonically frozen. They are awakened a thousand years later, when much of the Earth lies in ruins. A new black plague has killed most of the human population. The man uses what little scientific equipment that still exists to clone his cat and sends out the clones to fight against the disease-spreading rats.
  • An employee at a cryonics lab passes away. He returns as a ghost, wandering the rows and rows of frozen bodies. He discovers that he can thaw out a body, possess it, and live the frozen person’s life for a day before anyone notices the body is gone.
  • A man has himself cryonically preserved, hoping to be revived when a cure for cancer is found. He is awakened a thousand years in the future, after most of humanity has been destroyed by war. He discovers that he is the last preserved person on Earth. For hundreds of years, people have told stories and sang songs about the mysterious, frozen man and who he might be. He decides to make up a life story worthy of legend.
  • A banker opens an old and abandoned safety deposit box and finds a cryonically frozen human fetus. Unable to conceive, she looks for a doctor willing to implant the fetus into her womb.
  • A group of alien archeologists discover a cryonic suspension facility with dozens of frozen humans. At least, most of them are humans. One of them has bone white skin, a red smile, and ridiculously huge shoes. The aliens wake up this strange creature and discover it only communicates by honking a bicycle horn. He doesn’t seem interested in helping with their research, just playing pranks and throwing pies. Why did they freeze him with pies?!?
  • To escape a nuclear war, scientists build a cryonics lab in a cave deep underground. Hundreds of people are frozen to wait for a time when the surface is habitable again. Three centuries later, they begin to wake up. They are not alone. The cave system is filled with the eggs of a huge creature, some lizard mutated by the nuclear radiation. The eggs begin to hatch…
  • A man marries a beautiful, young woman and forces her into a cryonic chamber, only letting her out when he wants her. He gets older, but his wife is kept in pristine condition.
  • A man is told he has an incurable disease, so he elects to be frozen until a cure is discovered. While he sleeps, he is abducted by aliens. He is revived a thousand years later, on an alien world.
  • A team of archeologists discovers a cryonic prison. The world’s most dangerous criminals have been lying there, frozen, for hundreds of years. In the middle of the prison, in suspended animation, is an eight-year-old girl. The archeologists begin to debate: Was she frozen in some sort of tragic mistake, or did the government have a good reason for wanting her out of the way?
  • A woman discovers that the statues at her museum are actually alive, humans who have been frozen in an ancient form of cryonics.
  • A scientist builds a cryonic suspension chamber so his family’s dog will stay a puppy for decades. His wife begins to have strange ideas about the new baby…
  • In the distant future, archeologists revive preserved humans, gathering knowledge about the past. As the earth is overcrowded, any useless humans are killed. A gambler and con artist convinces the scientists that he is filled with useful information.
  • Too afraid to take his own life, a depressed man purchases a cryonic freezing chamber and searches for the perfect place to sleep until the end of time.
  • A teenage boy with a rare disease has to be cryonically frozen until a cure is discovered. He is awakened twelve years later and cured. Coming home from the hospital, he finds that his best friend and high school sweetheart have grown into adults, and his brother, who he last remembers in diapers, is now the same age as him.
  • A man volunteers to take part in a new cryonic freezing process, being frozen and revived a year later. He is frozen but, horrifically, he is conscious but unable to move. Before he can be revived, the earth is hit by World War III.
  • A young man with a rare disease agrees to be frozen until the doctors can find a cure. He is placed in suspended animation but, due to a technical glitch, he remains conscious. He remains frozen for decades, with nothing to do but think. To avoid going insane, he constructs an entire world in his mind, imagining hundreds of people, their lives, families, pets, and more. Two hundred years later, he is finally thawed out and cured. He goes from being the god of an imaginary world to an ordinary human, unemployed and friendless. Needless to say, the adjustment is difficult.
  • During the Great Depression, tens of thousands of people volunteer to be cryonically preserved, hoping to be thawed out when the economy recovers.

Resurrection – I’ll Be Back

  • The dictator of a small country is assassinated. Before news of his death reaches the public, his doctor brings him back to life. A few days later, he is assassinated again. Once more, the doctor restores him to life. The assassins try gunshots, poison, drowning, hanging, dismemberment, but nothing seems to work. When the dictator reappears again, the assassins try their most creative method yet.
  • An elderly scientist brings his wife back from the dead. She wakes up to find herself still trapped in her body, still afflicted with chronic pain. While the scientist attempts to cure her, she searches for a way to die permanently.
  • A scientist uses his new resurrection machine to bring his suicidal wife back to life again and again and again…
  • A tiny country’s only weapon is a resurrection machine. When they are invaded, they use the machine to bring back the enemy’s dead… Everyone who has ever died in the enemy nation comes back.
  • In an overcrowded future, you have to fill out an application with the government to get a friend or relative brought back from the dead. However, the government does not want the population to rise. If your application is approved, you are assigned someone to kill.
  • A man can come back from the dead, but loses his memory each time. He begins to wonder if it’s really “him” that comes back.
  • A cult leader uses his resurrection machine to perform a “miracle”
  • A machine which allows you to keep your old personality, memory after reincarnation leads to the birth of a new religion
  • A scientist uses a resurrection machine to bring his wife back from the dead. The machine is switched on, and her spirit is yanked from heaven and thrust into her sixty-year-old, arthritic body. She opens her eyes and sees her balding, sweaty, unshaven husband standing over her. She is not exactly happy to be back.
  • A dangerous medical treatment is tested on death row prisoners, with disappointing results. But years later, the graveyard is disturbed, and dozens of murderers begin rising from the grave.
  • A young doctor working in the county morgue develops a machine that can return the dead to life. Unfortunately, his machine can only transfer life from the dead to the living. Any time he brings someone back from the grave, someone else has to take their place.
  • A woman is brought back to life by a strange, ghostly pale scientist. The scientist explains that his machine relies on the “balance between the living and the dead.” He explains that, if she wants to stay alive, she must convince someone else to commit suicide within 48 hours.

Physical Changes

Shrinking – Bankrupt Shrink Ray Company Faces Massive Downsizing

  • A man discovers a shrunken city inside a snow globe-like bubble. When he falls in love with one of the city’s diminutive inhabitants, he becomes determined to find a way to live there.
  • A big game hunter funds the development of a shrink ray so he can experience the thrill of hunting spiders, scorpions, and other dangerous insects.
  • When funding for his shrink ray research is cut, a physicist kidnaps his boss and shrinks him. The physicist drops his boss in a terrarium with a hungry tarantula. His boss looks for a way to escape before he is eaten alive.
  • Aliens invade the Earth, blasting the military with shrink rays. An Air Force pilot in an inch-long fighter jet searches for a way to defeat the aliens and restore everyone to their rightful size.
  • An office worker invents a shrink ray and uses it to get rid of his annoying coworkers. After they are shrunk, he takes them home and locks them in a doll house. They want to escape, but the doll house is guarded by a hungry cat.
  • After the invention of shrink ray technology, some women rent themselves out as living toys. They pose on their client’s shelves, play in doll houses, and take rides in remote control cars. When an obsessive client refuses to return one of his “toys”, she must find a way to escape his clutches or risk being doll-sized forever.
  • To cope with prison overcrowding, a team of scientists develops a shrink ray to reduce prisoners to the size of action figures. The prisoners are horrified when they discover that they can never be returned to their normal size.
  • After an accident with a shrink ray, a now tiny super villain struggles to be taken seriously. Even when he threatens the world with a doomsday device, the heroes and news media just mock him. He decides that if he can’t reverse the shrinking process, he’ll find another way to make himself bigger.
  • A shrink ray is used on humans as part of the new extreme sport: spider wrestling.
  • The children at an elementary school discover a shrink ray and use it to take over the town.
  • Variation – The wife of an inventor runs a daycare from her home. When the children discover her husband’s shrink ray, they decide that naptime is over.
  • A hospital maternity ward uses a shrink ray on fetuses to make childbirth completely painless. Unfortunately, one out of every hundred kids can’t be re-enlarged
  • The world’s most dangerous industrial spy is also the world’s smallest man. The thief shrinks himself to the size of a mouse and steals prototype microchips from research companies.
  • A Senator proposes an unusual solution to America’s overcrowded prisons: shrinking the prisoners to the size of ants.
  • The government’s secret weapon is an assassin who is only three inches tall. Too small to handle a gun, he has to secretly drop poison pills into his target’s drink.
  • After hearing scratching in the walls, an elderly couple calls an exterminator. The exterminator discovers that the noises are not caused by mice or insects, but by tiny people. There is an entire city behind the drywall.
  • An elderly inventor gives his granddaughter a beautiful dollhouse. When she complains that there are no dolls inside, he shows her how to make some… by shrinking her parents.
  • Variation – When his son and daughter-in-law decide to get divorced, an elderly inventor decides to force them to live together until they work out their differences. He shrinks them down and locks them inside his granddaughter’s dollhouse.

Enlarging – Broadening Your Horizons

  • A farmer loses his arms in a tragic accident. A doctor grows him new cloned limbs. The transplant is a success, and the farmer returns home. After a few days, he notices his shirt sleeves seem too short. His arms are still growing. And growing. And growing…
  • After an alien invasion, the earth’s major cities are destroyed and the surviving humans are enslaved. Everything looks bleak until a young girl discovers the alien’s enlarging ray.
  • After the earth beings its terraforming project on a new planet, they need an inexpensive way to shape the new landscape. With the help of an enlarging ray, a team of six giant men set to building mountains and islands and digging rivers.
  • A team of astronauts makes a trip to a distant planet and, after they don’t return, they are presumed lost. Years later, astronomers are astonished as a great mass of stars are blacked out by a colossal object entering the solar system: a man the size of a planet. The captain of the astronauts has survived.
  • The government gets word of a strange terrorist plot. A man who can expand his size is headed for the nation’s capital. If he reaches Washington before they catch him, he’ll grow to a hundred times his normal size and destroy it.
  • A mad scientist with an enlarging ray breaks into a zoo and enlarges all the animals to fifty times their size.
  • A truck carting chemical waste overturns near a pet store. A little girl buying a kitten is horrified when her kitty jumps from her arms and runs to the pool of glowing liquid. Soon, the entire city is in danger from a hundred-foot kitten.
  • An overweight man is given a new weight loss treatment by his doctor. The treatment changes his metabolism so that, instead of growing wider, he grows taller.
  • After a truck shipping radioactive waste overturns on the highway, a nearby preschool is evacuated. An anxious mother comes to pick up her daughter and she is shocked to find that her little girl isn’t so little anymore.

Age Change – Pressing Rewind

  • Scientists theorize that the reason for all crime is poor parenting. They take some volunteers from a prison and de-age them back to children so they can get a second chance at being raised properly. As no one would want to take hardened criminals into their home, their adoptive parents are not told about the program.
  • A starship on a long journey keeps the passengers alive through a cutting edge medical treatment that reverses the aging process. As they are approaching their destination, the passengers are de-aged one last time. A woman is shocked to find herself de-aged back to a preteen.
  • A couple learns that their child has a rare genetic condition that will kill her by the time she turns sixteen. The condition is incurable, but there is a treatment: stopping the aging process.
  • Each time a vampire feeds, the blood rejuvenates them, reversing the aging process. By carefully spacing out their meals, they can stay the same age forever. A particularly gluttonous vampire feeds too much over a long night and finds himself de-aged to a preteen.
  • A rebellious nineteen-year-old refuses to get a job, so her scientist mother makes her too young to need one
  • A politician decides to clean up the homeless in his city by kidnapping them, regressing them back to infancy, and then dropping them off at the local orphanage.
  • Variation – Prospective parents, worried that their future children won’t grow up to be good people (or attractive people, or intelligent people) come to an unusual orphanage – Perspective parents describe their ideal child and orphanage employees look for an adult who matches. The adult is turned into a small child and adopted.
  • Another variation – A thirty-year-old man is paid a visit by the doctor who delivered him when he was born. The doctor informs him that, as the man is a failure as an adult, he has to come back to the hospital to be born again.
  • A boarding school has an unusual policy: fail your classes and you repeat a grade… and repeat a year of your life.
  • The local media ignores strange rumors of vampires controlling their city until the high school hires a new principal and the seniors start looking like senior citizens.
  • After a scientist invents a rejuvenation pill, depressed and stressed adults return to their childhood to escape the pressures of being an adult. Soon, there is a severe shortage of parents.
  • A newlywed couple, unable to have children, visits a fertility clinic. The doctor announces that there is a problem with the husband’s sperm. Later, the doctor meets with the wife in private and tells her that there may be a way to have the baby she always wanted. Her husband is not too happy with her plan…
  • A new resort becomes very popular with high-stress executives. They travel to a tropical island where they can spend their two weeks vacation as a child
  • The CEO of Fluffy Diapers, Inc. decides that her company would make more money if babies didn’t grow up quite so fast…
  • Three brothers have no memory of their childhoods. They discover that their parents, wishing to avoid the troubles of raising infants, used chemical treatments to “fast forward” them to their teen years.
  • In the distant future, adults have grown to accept the totalitarian government, and only the young are idealistic enough to revolt. If adults attempt a rebellion, government soldiers regress them until they are too young to cause any trouble.
  • A college student develops the ability to control his age. Soon, he decides that he can escape the pressures of academia by returning to his preschool years. His parents try to force him to return to adulthood by throwing him out of the house, but he threatens to call Child Protective Services and have them arrested. They realize that he has the upper hand, and they may be forced to care for him for decades to come.
  • After graduating college, a young man wishes that he did not have to go to work. He gets his wish when he loses consciousness and wakes up in a retirement home.
  • A medical company approaches the government with a plan to eliminate prisons. Instead of criminals being locked away in jail, they could simply be regressed to childhood and re-raised. Unfortunately, even five-year-olds can commit crimes…
  • An eight-year-old girl keeps her favorite possessions in her tree house: her crayons, her tea set, and her book of black magic. One weekend, the girl is left alone with a babysitter. She uses her book of magic spells to regress her babysitter into an infant and keeps her as her living baby “doll.”
  • The government sends an age-changing spy to an orphanage to investigate rumors of abuse. When she is suddenly adopted, she begins to wonder if her adulthood has slipped away for good.
  • A scientist’s new job at a secret government laboratory is incredibly stressful. To help her relax, she uses the lab’s rejuvenation machine and spends her weekends as a teenager. When her coworkers discover her little hobby, they decide to make her too young to reach the controls.
  • A doctor cures his wife’s cancer with a special rejuvenation drug, making her age in reverse. Unfortunately, he can’t make her regression stop.
  • Variation – A young mother is devastated when her teenage son develops cancer. A doctor informs her that an experimental treatment may be able to save his life – by reversing the aging process. After the treatments are over, the mother decides that her son needs a babysitter. As his mind was unaffected, he does not agree, especially since the only babysitter in town is his ex-girlfriend.
  • Another variation – A brilliant scientist is working on a cure for cancer. Strangely, her cure works by reversing the aging process, taking the patients back to before the cancer developed. Late one night, she comes home from work and finds her teenage son selling drugs. She decides to take him to the lab and turn him back to the sweet, little boy he used to be.
  • A thirteen-year-old boy discovers that he used to be a thirty-year-old man. After he committed a brutal murder, he was forced to choose between the death penalty or taking part in an experimental program to reverse the aging process. He was regressed to an infant and re-raised by new parents, and now government agents watch him constantly, waiting to see if he kills again.
  • A dozen astronauts are recruited to take part in a top-secret government program. The government is building the first spaceship designed to travel to distant planets. However, in order to save money and resources, the astronauts will be shrunk. Smaller people will eat less, breathe less, and take up less space. However, the astronauts soon discover that they will not be “shrunk” so much as “regressed”…
  • In the near future, new parents can avoid the stress of diapers and midnight feedings. They can simply take their infants to Timebender’s Daycare. In seven short days, troublesome newborns are transformed into seven-year-old children.
  • In an effort to catch child molesters, the NYPD hires a team of shape-shifting adults to act as bait.

Sex Change – Ladies’ Night

  • A murderer is forced to replace his victim, to live the life she would have lived.
  • A man desperately wants to move to the new colonies on Mars but, unfortunately, the government has already filled the quota for male volunteers. The man talks to a local scientist, who has a strange solution to the problem.
  • A store in the middle of the Nevada desert offers an unusual service: instantaneous, reversible sex changes.
  • While researching the human genome, a brilliant, female scientist discovers a way to have the daughter she always wanted. Her son is not happy with her plan.
  • After losing a bet, a teenage boy is forced to dress as a girl for Halloween. He goes to a thrift store and finds a prom dress that fits perfectly. The dress was owned by a young girl who died before she got to go to prom. The girl’s ghost is shocked to find that the dress is once again filled by a warm body. She decides that, one way or another, she will go to the prom after all.
  • A man is dying of a terminal disease. The doctors inform him that, since his brain is healthy, it can be transplanted into a new body. All they have to do is wait for a donor. Months later, a different patient dies of brain cancer. The patient’s tissue and blood type is a match. Unfortunately, the donor is a woman. The man must choose between death or giving up his gender.
  • As part of an experimental government program, students at a local high school are forced to take a Gender Aptitude Test. Anyone not scoring high enough in their own gender is reassigned, wither they like it or not.
  • Medical researchers working for plastic surgeons develop a virus that can alter DNA, transforming an average woman into a perfect beauty. Unfortunately, the virus does not die off as quickly as they thought, and the newly beautiful women infect their mates.
  • As a joke, a young man fills out an application for Miss Congeniality’s Charm School. When he is accepted, he decides to continue the joke and shows up for the first day of class. To his horror, he discovers that he will be made into a polite, young lady, whether he likes it or not.
  • A lonely teenage boy is given a magical ring that allows him to become a superhero whenever he puts it on. Unfortunately for him, that superhero is Fantastic Girl.
  • In the eighteenth century, one young woman longs to join the navy and see the world. But, alas, only men may become sailors. She visits her uncle, an early scientist, and explains her problem. After months of work, he produces a potion which, he says, will turn her into a male for thirty day. It works! She takes two dozen bottles of the potion and joins the navy. Three weeks later, her ship strikes a rock and sinks. She and six of the crew are the only survivors. They swim to a nearby island and wait to be rescued. All the extra bottles are at the bottom of the sea. Shuddering in fear, she realizes that, if she can’t recover the bottles, she’ll be the only woman on an island full of sailors.
  • Variation – In the eighteenth century, one young woman longs to join the navy and see the world. But, alas, only men may become sailors. She visits her uncle, an early scientist, and explains her problem. After months of work, he builds a machine which he uses to transform her into a male. After several years at sea, she returns to her uncle’s house so she can be restored, but he has passed away and his equipment has been sold. She searches the city for his machine knowing that, if she can’t find it, she will be stuck as a man forever.
  • Another variation – For generations, all the males in the Smith family have bean sailors. John Smith refuses to join the navy, so his father beats him. The day before his eighteenth birthday, John Smith knows he must do something drastic to avoid being sent out to sea. He visits his uncle, an early scientist, who has the solution: a potion which will turn him into a woman.
  • While searching the internet for information on “mail order brides,” a man comes across an unusual website. Unfortunately, the website is based overseas, and the English translation is very poor. The website asks “Alone in your house? You wish a woman be coming? Select a picture, and you see her face soon.” After placing his order, he does see a new face… in his bathroom mirror.

Human to Animal – Dog Days

  • A young man, obsessed with horror movies, heads into the woods to hunt werewolves. Something jumps out of the bushes and bites him on the leg. The young man is disappointed to discover that he is now a werepoodle.
  • A bankrupt businessman decides to take his own life, jumping from the top of a skyscraper. On the way down, he changes his mind and prays for salvation. The next day, his wife notices a pigeon that seems to be following her…
  • A geeky college student falls in love with a cheerleader. Desperate to get close to her, he convinces his pre-med student friends to switch his brain with that of the cheerleader’s dog.
  • A small child runs away from home and heads for his favorite place: the local zoo. A mad scientist zookeeper offers to let the child stay at the zoo forever.
  • A forest ranger discovers a feral child who was raised by wolves and takes him to an orphanage. Ten years later, the feral boy returns to the woods where his wolf “parents” offer to make him truly a part of their family.
  • A man with the ability to change into animals loses his job. Unable to find new employment, his landlord evicts him. Desperate, he turns to the only place where he knows he can stay for free: the city zoo.
  • A young woman, spying on her boyfriend, sees him change into a wolf. Horrified, she decides that the future of their relationship depends upon one thing: which was he originally? Man or animal?
  • An archeologist who accidentally swallows a fossil gains the ability to change into any dinosaur he likes.

Strange Changes – Let’s Get Weird

  • A scientist discovers ancient nematodes, still alive and frozen under the arctic ice. When he thaws them out, he is infested with the parasites, gaining the memories of a long-extinct humanoid species. He vows to infest more people, letting the ice creatures rule again.
  • After angering a local witch doctor, an anthropologist’s body slowly turns to cloth. He must find a cure before he becomes a living doll.
  • A lonely man falls in love with a department store mannequin, and comes to visit “her” every day. When a male mannequin appears next to her in the store window, the man searches for a way to take his place.
    A woman, obsessed with holographic movies, becomes just like her favorite stars: an intangible projection, a beauty made of light.
  • A homeless man falls asleep in the city park. Waking up the next morning, he finds that his feet are stuck to the ground. He has sprouted roots. Examining his feet, he finds that his ankles are covered in bark. Slowly, painfully, he transforms.
  • An astronaut visiting an alien world contracts a disease that destroys his skin. The alien doctors decide to replace his skin with steel.
  • A beautiful surfer is attacked by sharks and her legs are torn from her body. Bleeding in the water, she is rescued by dolphins, who take her to their secret city at the bottom of the sea. The dolphins explain that their surgeons can save her life, but they can’t replace her legs. The surfer is faced with a choice: return to dry land as a disabled woman or be surgically transformed into a mermaid.
  • A young woman takes a job at Hades’ Ladies, a strange strip club where the performers paint their skin red and wear horns and fake tails. After her first night on the job, she finds that some costumes are impossible to remove…
  • During the gold rush in 1849, a greedy prospector discovers an ancient book on alchemy that describes how to make a chemical mixture that can turn anything into gold. After spilling the potion on himself, the gold-skinned man is hunted by every prospector in California.
  • Four college students rent a large house together. The house, having been built in the 1950’s, has very old-fashioned ideas about who should live inside of it. It wants a traditional nuclear family. Soon, the four students find themselves going through some very strange changes.
  • A strange cult grows in popularity: the Mannequinists. Their slogan: “Stillness is bliss!”
  • A scientist offers his new lab assistant the opportunity to be transformed into a superhero called “Granite Man.” He accepts, and begins learning to use his newfound powers. Unfortunately, he soon discovers that there have been dozens of “Granite Men” before him, and each incarnation of the superhero has been killed… on their first day in the field… by the same villain.
  • In a bizarre accident, a trench coat-wearing “flasher” is transformed into an incorporeal hologram. He can flash anyone, and the police are unable to stop him.

Let's keep in touch.

Get my monthly newsletter for the latest posts, book releases, and giveaways!

We don’t spam! Read our privacy policy at https://dnschmidt.com/privacy-policy for more info.

Leave a Comment

Your email address will not be published. Required fields are marked *